Echo Virus Type 9 Observed in Electron
نویسندگان
چکیده
Cytopathic changes induced in tissue cultures by a variety of enteroviruses have been observed in the light microscope (1-5). Furthermore, detailed analysis by means of electron microscopy has revealed the presence of intracytoplasmic crystalline viral aggregates (6-11) as well as alterations in the fine structure of cells infected by some of these agents (12). A preliminary study of type 9 E C H O virus (1) has demonstrated viral particles in a regular, although non-crystalline, arrangement upon a series of parallel filaments within the cytoplasm of cells manifesting the characteristic enteroviral cytopathic effect. The purpose of this paper is to describe the structure of E C H O 9 virus, the manner in which it develops and the mechanism whereby it gains egress from the infected tissue culture cells.
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